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how not to design an experiment

On the Panda's Thumb today I read a review of a very poor experimental set-up indeed. Apparently demonstrating that beneficial mutations (here, antibiotic resistance) lower the fitness of the organism possessing them, it actually does no such thing because of the multiple flaws in its design. But read the review - the reviewer (ERV) studies virology & microbiology & so does a much better job than I could :-) This really is an excellent exercise in critical thinking.

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