Breadcrumbs

Associate Professor Michele R. Prinsep

Associate Professor (Organic Chemistry)

Qualifications: BSc(Hons) Canterbury, PhD. Canterbury, Post-doctoral Research Fellow, University of Hawaii (1990-1991). Research leave Cambridge (1994), ZONTA Award (2000).

Research Interests

  • Natural products chemistry, particularly that of New Zealand marine bryozoans and terrestrial cyanobacteria (blue-green algae).
  • Application of spectral methods, especially NMR spectroscopy and MALDI-TOF mass spectrometry to structural determination.
  • Biologically active compounds and structure-activity relationships.
  • Chemical ecology.

Current projects are directed towards finding novel and/or bioactive metabolites from New Zealand and Antarctic bryozoans and cyanobacteria.

Research Supervised

PhD

  • Kaufononga, Sangata (in progress). Indole-diterpenoid secondary metabolites produced by the Epichloe festucae var lolii-Lolium perenne symbiosis.
  • Omar, Syaliza (2013). Identifying iron-binding antioxidants in New Zealand honeydew honey. (chief supervisor Peter Molan).
  • Puddick, Jonathan (2013). Spectroscopic investigations of oligopeptides from aquatic cyanobacteria: Characterisation of new oligopeptides, development of microcystin quantification tools and investigations in microcystin production.

MSc (Research)

  • Shrubsall, Jacob (in progress). Novel brominated alkaloids from the bryozoan Amathia citrina.
  • Webb, Nicola (2015). Chemical ecological insights into metabolites of the New Zealand marine sponge, Cliona celata.
  • Wang, Alice (2015). Elucidating the modes of action of the antitumour New Zealand marine natural product Pterocellin A.

MSc

  • Kaufononga, Sangata (2014). Isolation and characterisation of Aeruginosin and microviridin variants from Microcystis species CAWBG11.
  • Rogers, Shelley (2014). Investigation of microcystin processing, production and export by Microcystis sp.
  • Hales, Richard (2013). Natural product analysis of coastal marine species of New Zealand.
  • Andersen, Aaron (2011). Investigations of natural products from Bryozoa inhabiting Aotearoa New Zealand.

BSc (Hons)

  • Dean, Lewis (2016). The natural products and chemical ecology of NZ Bryozoa and Nudibranchs.

Teaching Commitments

Recent Publications

  • Prinsep, M. R., Appleton, T. G., Hanson, G. R., Lane, I., Smith, C. D., Puddick, J., & Fairlie, D. P. (2017). Tolyporphin macrocycles from the cyanobacterium Tolypothrix nodosa selectively bind copper and silver and reverse multidrug resistance. Inorganic Chemistry, 56(10), 5577-5585. doi:10.1021/acs.inorgchem.6b03000

  • Prinsep, M. R., Dean, L. J., Fairweather, R. M., Crombie, C., Shrubsall, J., & Leonard, K. (2017). Applications of Liquid Chromatography-Mass Spectrometry (LC-MS) to natural products explorations of New Zealand marine invertebrates. In 2nd Queensland Annual Chemistry Symposium (QACS) 2017. Conference held at Queensland University of Technology, Brisbane, Queensland, Australia.

  • Prinsep, M. R. (2017). Chemical ecology of New Zealand marine bryozoans: current knowledge and future directions. In AustraLarwood VII Bryozoan Symposium. Held in Wellington, New Zealand.

  • Browne, A., Clearwater, M., Prinsep, M., Battershill, C. N., & Vanneste, J. (2017). Novel New Zealand marine bioactive nature products for the control of Psa biovar 3. Poster session presented at the meeting of Blue2Green Marine Biotechnology Convention 2017. Conference held in Tauranga, New Zealand.

View All research publications by Michele Prinsep

Contact Details

Email: michele@waikato.ac.nz
Room: E.3.06
Phone: +64 7 837 9392