Dr Joanna McKenzie
Postdoctoral Fellow
Qualifications: PhD MSc (Hons) BSc (Waikato)
Research Interests
Protein Biochemistry and Molecular Biology.
Investigation of the role of VapBC proteins in mycobacteria. The Mycobacterium tuberculosis genome contains 45 genes encoding VapBC proteins. We aim to understand the role of these proteins in the mycobacteria species.
Recent Publications
- Ahidjo, B., Kuhnert, D., McKenzie, J., Machowski, E., Gordhan, B., Arcus, V., Abrahams, G., Mizrahi, V. (2011) VapC toxins from Mycobacterium tuberculosis are ribonucleases that differentially inhibit growth and are neutralized by cognate VapB antitoxins
Refereed Journal Articles - Plos ONE - Arcus, V., McKenzie, J., Robson, J., Cook, G. (2011) The PIN-domain ribonucleases and the prokaryotic VapBC toxin–antitoxin array
Refereed Journal Articles - Protein Engineering, Design and Selection - Robson, J., McKenzie, J., Cursons, R., Cook, G., Arcus, V. (2009) The vapBC Operon from Mycobacterium smegmatis is an autoregulated toxin - antitoxin module that controls growth via inhibition of translation
Refereed Journal Articles - Journal of Molecular Biology - Bunker, R., McKenzie, J., Baker, E., Arcus, V. (2008) Crystal structure of PAEO151 from Pyrobaculum aerophilum, a PIN-domain (VapC) protein from a toxin-antitoxin operon
Refereed Journal Articles - Proteins: Structure, Function and Bioinformatics
